Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174988 | 0.85 | NR1I2 (0.39) | CCR1CCR5CCR8KDM4E | |
| SCHEMBL11801461 | 0.82 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL5974098 | 0.80 | NR1I2 (0.47) | CCR1CCR5CCR8KDM4E | |
| SCHEMBL175672 | 0.79 | CCR1 (0.38) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL23914094 | 0.76 | KDM4E (0.48) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| Bromide SCHEMBL2514869 | 0.76 | CCR1 (0.35) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| Dipyridyl SCHEMBL28135789 | 0.74 | KDM4E (0.64) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL22458264 | 0.74 | NR1I2 (0.37) | KDM4E | |
| SCHEMBL145233 | 0.74 | CCR1 (0.33) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL22298873 | 0.74 | LOXL2 (0.39) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988331-B1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | PROMERUS LLC (US) | 2004-09-01 | — | — | EP | disclosed |
| US-6265506-B1 | AMORPHOUS COPOLYMERS | THE B. F. GOODRICH COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-0988331-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056839-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |