Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907192 | 0.82 | AKR1C3 (0.47) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL3818255 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL83065 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL3485765 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| Ammonia Solution, Strong SCHEMBL4743624 | 0.77 | ABCG2 (0.56) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL8351839 | 0.77 | AKR1C3 (0.53) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL10437231 | 0.77 | AKR1C3 (0.53) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL6553166 | 0.76 | AKR1C3 (0.52) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL11419990 | 0.76 | ALDH1A1 (0.42) | AKR1C3AKR1C1MEN1KMT2AHTT | |
| SCHEMBL2554162 | 0.76 | AKR1C3 (0.52) | AKR1C3AKR1C1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3563826-B1 | WATER-IN-OIL TYPE COSMETIC EMULSION PREPARATION | SHISEIDO CO LTD (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-11540998-B2 | Water-in-oil emulsion cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2023-01-03 | — | — | US | disclosed |
| US-11213472-B2 | VEGFC production promoter | SHISEIDO COMPANY, LTD. (JP) | 2022-01-04 | — | — | US | disclosed |
| EP-2902022-B1 | VEGFC PRODUCTION PROMOTER | SHISEIDO CO LTD (JP) | 2020-10-28 | — | — | EP | disclosed |
| US-20200222294-A1 | VEGFC PRODUCTION PROMOTER | SHISEIDO COMPANY, LTD. (JP) | 2020-07-16 | — | — | US | disclosed |
| US-10624829-B2 | VEGFC production promoter | SHISEIDO COMPANY, LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-10470989-B2 | Surface-treated powder using theanine, and cosmetic preparation containing same | KOSE CORPORATION (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20170281500-A1 | VEGFC PRODUCTION PROMOTER | SHISEIDO COMPANY, LTD. (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20160271032-A1 | SURFACE-TREATED POWDER USING THEANINE, AND COSMETIC PREPARATION CONTAINING SAME | KOSE CORPORATION (JP) | 2016-09-22 | — | — | US | disclosed |
| US-20150328137-A1 | VEGFC PRODUCTION PROMOTER | SHISEIDO COMPANY, LTD. (JP) | 2015-11-19 | — | — | US | disclosed |
| EP-1416016-B1 | Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone | SHINETSU CHEMICAL CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20070207176-A1 | Powder treated with a power treating agent comprising an organopolysiloxane and cosmetic comprising the powder | SHIN-ETSU CHEMICAL CO., LTD. | 2007-09-06 | — | — | US | disclosed |
| EP-1829524-A2 | Organopolysiloxane powder treating agent, power treated with the agent and cosmetic comprising the powder | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20060165629-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20050129618-A1 | Drugs for ameliorating itch, rough skin or hypersensitive skin or for whitening via inhibition of the production and release of stem cell factor | SHISEIDO CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1457780-A1 | DRUGS FOR AMELIORATING ITCH, ROUGH SKIN OR HYPERSENSITIVE SKIN OR FOR WHITENING VIA INHIBITION OF THE PRODUCTION AND RELEASE OF STEM CELL FACTOR | SHISEIDO COMPANY LIMITED (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1416016-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-0615741-B1 | Oil-in-water type emulsion composition | SHISEIDO CO LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5693255-A | AMPHIPHILE AND SURFACTANT WHICH CAN FORM A GEL | SHISEIDO CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0615741-A1 | Oil-in-water type emulsion composition | SHISEIDO COMPANY LIMITED (JP) | 1994-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165629-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same | SPECC1L, FANCD2, ALG1 | AKR1C3 931/4885AKR1C1 1060/4885MEN1 2818/4885 |
| US-20150328137-A1 | VEGFC PRODUCTION PROMOTER | VEGFA, LRBA, NOS3 | AKR1C3 317/4885AKR1C1 248/4885MEN1 3736/4885 |
| US-10624829-B2 | VEGFC production promoter | VEGFA, LRBA, NOS3 | AKR1C3 317/4885AKR1C1 248/4885MEN1 3736/4885 |
| US-20170281500-A1 | VEGFC PRODUCTION PROMOTER | VEGFA, LRBA, NOS3 | AKR1C3 317/4885AKR1C1 248/4885MEN1 3736/4885 |
| US-11213472-B2 | VEGFC production promoter | VEGFA, LRBA, NOS3 | AKR1C3 317/4885AKR1C1 248/4885MEN1 3736/4885 |
| US-20200222294-A1 | VEGFC PRODUCTION PROMOTER | VEGFA, LRBA, NOS3 | AKR1C3 317/4885AKR1C1 248/4885MEN1 3736/4885 |
| US-20070207176-A1 | Powder treated with a power treating agent comprising an organopolysiloxane and cosmetic comprising the powder | RAD54L, H1-3, H1-0 | AKR1C3 2335/4885AKR1C1 2731/4885MEN1 1752/4885 |
| US-11540998-B2 | Water-in-oil emulsion cosmetic | H1-0, H1-5, SQLE | AKR1C3 3713/4885AKR1C1 3054/4885MEN1 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.