Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912224 | 0.89 | KMT2A (0.34) | TLR8KDM4EHASPINLMNAMAPT | |
| SCHEMBL6911625 | 0.80 | TLR8 (0.46) | TLR8KDM4EABL1RIN1HASPIN | |
| SCHEMBL48603 | 0.78 | ALDH1A1 (0.34) | MAPTALDH1A1POLB | |
| SCHEMBL10573069 | 0.78 | TLR8 (0.40) | TLR8KDM4EABL1RIN1HASPIN | |
| SCHEMBL5522764 | 0.77 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL11051079 | 0.77 | TLR8 (0.42) | TLR8KDM4EABL1RIN1SMN1; SMN2 | |
| SCHEMBL8763662 | 0.74 | TLR8 (0.42) | TLR8KDM4EABL1RIN1HASPIN | |
| SCHEMBL10839342 | 0.72 | MAPT (0.36) | SMN1; SMN2LMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL1797285 | 0.72 | — | — | |
| SCHEMBL6911477 | 0.71 | ALDH1A1 (0.32) | KDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265940-B1 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBERMARLE CORP (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1265940-B1 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBERMARLE CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6509434-B1 | Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas | ALBEMARLE CORPORATION | 2003-01-21 | — | — | US | disclosed |
| EP-1265940-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | Albermarle Corporation (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070841-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBEMARLE CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0570798-A1 | Use of alkylthio-substituted aromatic diamines as a curing agent for polyisocyanates in coating compositions or jointing compounds | BAYER AG (DE) | 1993-11-24 | — | — | EP | disclosed |