Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914733 | 1.00 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2TSHRMAPT | |
| SCHEMBL6904297 | 0.90 | GRM2 (0.43) | TAS1R3TAS1R1MAPTNPSR1ALDH1A1 | |
| SCHEMBL6904292 | 0.90 | GRM2 (0.43) | TAS1R3TAS1R1MAPTNPSR1ALDH1A1 | |
| SCHEMBL6909803 | 0.89 | GRM2 (0.36) | TAS1R3TAS1R1TAS1R2TSHRMAPT | |
| SCHEMBL6909800 | 0.89 | GRM2 (0.36) | TAS1R3TAS1R1TAS1R2TSHRMAPT | |
| SCHEMBL6906235 | 0.89 | GRM2 (0.47) | TAS1R3TAS1R1MAPTALDH1A1GRM2 | |
| SCHEMBL6906238 | 0.89 | GRM2 (0.47) | TAS1R3TAS1R1MAPTALDH1A1GRM2 | |
| SCHEMBL6913679 | 0.88 | GRM2 (0.37) | TAS1R3TAS1R1TSHRNPSR1ALDH1A1 | |
| SCHEMBL6913681 | 0.88 | GRM2 (0.37) | TAS1R3TAS1R1TSHRNPSR1ALDH1A1 | |
| SCHEMBL6911124 | 0.88 | GRM2 (0.38) | TAS1R3TAS1R1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |