Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440323 | 0.82 | — | — | |
| SCHEMBL31679535 | 0.77 | CYP2A6 (0.43) | TSHR | |
| SCHEMBL353175 | 0.71 | TSHR (0.36) | TSHR | |
| SCHEMBL16365929 | 0.70 | PNMT (0.42) | — | |
| SCHEMBL152117 | 0.70 | TSHR (0.46) | TSHR | |
| SCHEMBL62944 | 0.70 | TSHR (0.46) | TSHR | |
| SCHEMBL151022 | 0.70 | TSHR (0.46) | TSHR | |
| SCHEMBL29617488 | 0.67 | TSHR (0.43) | TSHR | |
| SCHEMBL8890 | 0.67 | TSHR (0.48) | TSHR | |
| SCHEMBL154827 | 0.64 | SIGMAR1 (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022335-A1 | Novel polypeptides and methods for their use | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2003-01-30 | — | — | US | claimed |
| WO-2000037480-A1 | NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2000-06-29 | — | — | WO | claimed |
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| US-6794167-B2 | PROTEIN COMPLEX FOR USE IN THE BIOSYNTHESIS OF PREFERENTIAL COMPOUNDS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-09-21 | — | — | US | disclosed |
| US-20030022335-A1 | Novel polypeptides and methods for their use | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2003-01-30 | — | — | US | disclosed |
| WO-2000037480-A1 | NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2000-06-29 | — | — | WO | disclosed |