SCHEMBL6910044

SCHEMBL6910044

[SiH3]C1CC=CC2c3ccccc3CC12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.40
PTPN7 P35236 4/20 0.37
HSPA1A P0DMV8 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
ALOX15 P16050 2/20 0.35
MAPK1 P28482 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAPDH P04406 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157232 0.84 PTPN7 (0.43) KDM1APTPN7HSPA1ATDP1MAPT
SCHEMBL13973267 0.79 KDM1A (0.47) KDM1APTPN7HSPA1ATDP1MAPT
SCHEMBL5616843 0.78 KDM1A (0.39) KDM1APTPN7HSPA1ATDP1MAPT
SCHEMBL61049 0.76 PTPN7 (0.38) KDM1APTPN7HSPA1ATDP1MAPT
Hydrochloric Acid SCHEMBL6303594 0.71 KDM1A (0.36) KDM1APTPN7HSPA1ATDP1MAPT
Hydrochloric Acid SCHEMBL7647947 0.71 KDM1A (0.33) KDM1APTPN7HSPA1ATDP1MAPT
SCHEMBL62523 0.68 HSPA1A (0.32) KDM1APTPN7HSPA1ATDP1MAPT
SCHEMBL3396441 0.64 KDM1A (0.39) KDM1AGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL202263 0.64 GRIN2D (0.35) KDM1AGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8077660 0.64 IDO1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412264-B Organometallic chain transfer agent 陶氏环球技术有限责任公司 2024-06-25 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-110612315-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-108026115-B Multi-head or double-head composition capable of being used for chain shuttling and preparation method thereof 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
EP-3902867-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2021-11-03 EP disclosed
EP-3902868-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2021-11-03 EP disclosed
CN-110612315-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-24 CN disclosed
CN-110603274-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110603271-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110582518-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-17 CN disclosed
CN-110546171-A catalyst system for forming multi-block copolymers DOW GLOBAL TECHNOLOGIES LLC 2019-12-06 CN disclosed
CN-101142247-A Pseudo-block copolymers and methods of using chain shuttling agents DOW GLOBAL TECHNOLOGIES INC (US) 2008-03-12 CN disclosed
CN-1954005-A Catalyst composition comprising shuttling agent for ethylene multi-block copolymer formation DOW GLOBAL TECHNOLOGIES INC (US) 2007-04-25 CN disclosed
EP-1421375-A2 METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2004-05-26 EP disclosed
WO-2003019176-A2 METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-06 WO disclosed
CN-1289343-A Improved olefin polymerization process DOW CHEMICAL CO (US) 2001-03-28 CN disclosed