SCHEMBL202263

SCHEMBL202263

C1=CC2c3ccccc3CC2CC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
KDM1A O60341 4/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
HTR2A P28223 6/20 0.33
HTR2C P28335 6/20 0.33
HTR2B P41595 6/20 0.33
HRH3 Q9Y5N1 5/20 0.33
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545658 0.98 GRIN2D (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7551766 0.98 GRIN2D (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24832561 0.76 ALDH1A1 (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8077660 0.70 IDO1 (0.42) SIGMAR1
SCHEMBL11666763 0.70 DRD2 (0.39) HTR2B
SCHEMBL2831438 0.70 DRD2 (0.39) HTR2B
SCHEMBL8157232 0.68 PTPN7 (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7625882 0.68 SIGMAR1 (0.40) HTR2AHTR2CHTR2BHRH3SIGMAR1
SCHEMBL8197745 0.67 CHRM2 (0.40) HRH3
SCHEMBL9300443 0.67 CHRNB2 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939456-B2 Composition for preparing a foam, foam, and shoe employing the same TSRC CORPORATION (TW) 2024-03-26 US claimed
CN-117736374-A Cyclic olefin composition and application thereof 杭州睿丰融创科技有限公司 2024-03-22 CN claimed
CN-117417512-A Cyclic olefin ring-opening polymer hydride for medical instrument and preparation method thereof 杭州睿丰融创科技有限公司 2024-01-19 CN claimed
CN-107735451-B Resin composition, resin molded article, and optical member 日本瑞翁株式会社 2022-12-27 CN claimed
CN-112867728-A Copper chelated (pyridylmethylene) butanediamine derivatives 冷泉港实验室 2021-05-28 CN claimed
EP-3823977-A1 (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER Cold Spring Harbor Laboratory (US) 2021-05-26 EP claimed
WO-2020018893-A1 (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER COLD SPRING HARBOR LABORATORY (US) 2020-01-23 WO claimed
US-20190023884-A1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC CORPORATION (TW) 2019-01-24 US claimed
EP-3431544-A1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC Corporation (TW) 2019-01-23 EP claimed
EP-1120389-B1 Preparation process of fluorenes JFE CHEMICAL CORP (JP) 2003-11-26 EP claimed
US-6344585-B2 DEHYDROGENATION OF THE CORRESPONDING TETRAHYDROFLUORENECOMPOUND ADCHEMCO CORPORATION (JP) 2002-02-05 US claimed
US-20010011144-A1 Preparation process of fluorenes ADCHEMCO CORPORATION (JP) 2001-08-02 US claimed
EP-1120389-A1 Preparation process of fluorenes Adchemco Corporation (JP) 2001-08-01 EP claimed
EP-1006134-A1 NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF NIPPON ZEON CO., LTD. (JP) 2000-06-07 EP claimed
EP-0900228-A1 A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-03-10 EP claimed
WO-1997041134-A1 A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-11-06 WO claimed
US-5670680-A Method for producing octahydrofluorenyl metal complexes THE DOW CHEMICAL COMPANY (US) 1997-09-23 US claimed
EP-0325260-B1 Random copolymer containing derivative of bicyclo (2.2.1) hept-2-ene compound NIPPON OIL CO LTD (JP) 1994-11-02 EP claimed
US-4931520-A Random copolymer containing derivative of bicyclo [2.2.1] hept-2-ene compound NIPPON OIL CO., LTD. (JP) 1990-06-05 US claimed
EP-0325260-A2 Random copolymer containing derivative of bicyclo (2.2.1) hept-2-ene compound NIPPON OIL CO. LTD. (JP) 1989-07-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010011144-A1 Preparation process of fluorenes AFF1, NAF1, RER1 GRIN2D 2269/4885GRIN3B 3153/4885GRIN1 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.