SCHEMBL61049

SCHEMBL61049

C[Si](C)(C1CC=CC2c3ccccc3CC21)C1CC=CC2c3ccccc3CC21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 6/20 0.38
HSPA1A P0DMV8 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
KDM1A O60341 4/20 0.37
MAPT P10636 5/20 0.36
KDM4E B2RXH2 3/20 0.36
HSD17B10 Q99714 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 2/20 0.36
MAPK1 P28482 2/20 0.36
MCL1 Q07820 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 2/20 0.33
GAPDH P04406 4/20 0.33
HSPA8 P11142 3/20 0.33
POLB P06746 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62523 0.81 HSPA1A (0.32) PTPN7HSPA1ATDP1KDM1AMAPT
SCHEMBL8157232 0.80 PTPN7 (0.43) PTPN7HSPA1ATDP1KDM1AMAPT
SCHEMBL13973267 0.76 KDM1A (0.47) PTPN7HSPA1ATDP1KDM1AMAPT
SCHEMBL6910044 0.76 KDM1A (0.40) PTPN7HSPA1ATDP1KDM1AMAPT
SCHEMBL5616843 0.74 KDM1A (0.39) PTPN7HSPA1ATDP1KDM1AMAPT
Hydrochloric Acid SCHEMBL7647947 0.71 KDM1A (0.33) PTPN7HSPA1ATDP1KDM1AMAPT
Hydrochloric Acid SCHEMBL6303594 0.71 KDM1A (0.36) PTPN7HSPA1ATDP1KDM1AMAPT
SCHEMBL7625415 0.61 HSPA1A (0.33) PTPN7HSPA1ATDP1MAPTKDM4E
SCHEMBL21189841 0.61 KDM1A (0.39) KDM1A
SCHEMBL3396441 0.61 KDM1A (0.39) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
US-12275810-B2 Telechelic polyolefins and processes for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-15 US disclosed
US-12180314-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-31 US disclosed
US-12129368-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-1066110-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM SILICATE OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 2001-01-10 EP disclosed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP disclosed
EP-1000093-A1 ZWITTERIONIC CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
EP-1000068-A1 PERFLUORONAPHTHYL SUBSTITUTED BORON CONTAINING CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
EP-1000069-A1 CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
WO-1999048605-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1999-09-30 WO disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed
WO-1999006449-A1 ZWITTERIONIC CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006413-A1 CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006412-A1 PERFLUORONAPHTHYL SUBSTITUTED BORON CONTAINING CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12129368-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PTPN7 4526/4885HSPA1A 3470/4885TDP1 1190/4885
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 PTPN7 3004/4885HSPA1A 3006/4885TDP1 570/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PTPN7 4526/4885HSPA1A 3470/4885TDP1 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.