Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | HSPA1A | P0DMV8 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 3/20 | 0.37 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910044 | 0.84 | KDM1A (0.40) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| SCHEMBL13973267 | 0.84 | KDM1A (0.47) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| SCHEMBL5616843 | 0.82 | KDM1A (0.39) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| SCHEMBL61049 | 0.80 | PTPN7 (0.38) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL7647947 | 0.75 | KDM1A (0.33) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL6303594 | 0.75 | KDM1A (0.36) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| SCHEMBL62523 | 0.71 | HSPA1A (0.32) | PTPN7KDM1AHSPA1ATDP1MAPT | |
| SCHEMBL3396441 | 0.68 | KDM1A (0.39) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL202263 | 0.68 | GRIN2D (0.35) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8077660 | 0.68 | IDO1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716092-B1 | Organic transition metal compound and process for the preparation of polyolefin using same | TOSOH CORP (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5770666-A | METALLOCENE | TOSOH CORPORATION (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0716092-A1 | Organic transition metal compound and process for the preparation of polyolefin using same | TOSOH CORPORATION (JP) | 1996-06-12 | — | — | EP | disclosed |