SCHEMBL6443296

SCHEMBL6443296

[O]C(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
RAB9A P51151 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2A6 P11509 1/20 0.47
ALOX5 P09917 1/20 0.46
TACR1 P25103 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
NPC1 O15118 2/20 0.44
MAPT P10636 1/20 0.44
NLRP3 Q96P20 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR7 P34969 1/20 0.44
HTR2B P41595 1/20 0.44
HTR3A P46098 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28936084 0.87 CYP1A2 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6443298 0.85 SLC1A3 (0.55) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL1321228 0.84 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL729692 0.84 ALDH1A1 (0.61) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6910495 0.84 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL6406854 0.84 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL30924172 0.84 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL487508 0.84 ALDH1A1 (0.61) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL2001872 0.84 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2
SCHEMBL28936085 0.82 CYP1A2 (0.54) SLC1A3SLC1A2SLC1A1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370751-B2 Sulfonium salt, heat- or photo-acid generator, heat- or photo-curable composition, and cured product thereof SAN APRO LTD. (JP) 2022-06-28 US disclosed
CN-109661601-B Polarizing plate and method for manufacturing same 住友化学株式会社 2022-02-01 CN disclosed
CN-109311915-B Sulfonium salt, thermal or photoacid generator, thermal or photocurable composition, and cured product thereof 三亚普罗股份有限公司 2021-09-14 CN disclosed
US-20190284134-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT- OR PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN APRO LTD. (JP) 2019-09-19 US disclosed
EP-3492476-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT-CURABLE OR PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF San-Apro Ltd. (JP) 2019-06-05 EP disclosed
US-9884882-B2 Method for producing thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate FUJIFILM CORPORATION (JP) 2018-02-06 US disclosed
EP-3109245-B1 METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORP (JP) 2018-01-03 EP disclosed
EP-3109245-A1 METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM Corporation (JP) 2016-12-28 EP disclosed
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORPORATION (JP) 2016-12-08 US disclosed
EP-2497475-A1 Treatment of laminitis with platelet aggregation inhibitors Dussler, Sabine (DE) 2012-09-12 EP disclosed
EP-0542411-B1 TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION SANKYO CO (JP) 1998-08-12 EP disclosed
US-5753652-A Antiretroviral hydrazine derivatives NOVARTIS CORPORATION (US) 1998-05-19 US disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
EP-0521827-B1 Pharmacological active hydrazin derivatives and process for their preparation CIBA GEIGY AG (CH) 1996-09-25 EP disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284134-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT- OR PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT THEREOF TST, MPST, ASIC1 SLC1A3 1585/4885SLC1A2 2012/4885SLC1A1 1386/4885
US-11370751-B2 Sulfonium salt, heat- or photo-acid generator, heat- or photo-curable composition, and cured product thereof TST, MPST, ASIC1 SLC1A3 1585/4885SLC1A2 2012/4885SLC1A1 1386/4885
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE ST6GAL1, FUT6, FUT5 SLC1A3 1421/4885SLC1A2 1227/4885SLC1A1 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.