SCHEMBL28936084

SCHEMBL28936084

O=C(OCc1ccc2ccccc2c1)C(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
RAB9A P51151 2/20 0.50
CYP2A6 P11509 1/20 0.48
ALOX5 P09917 2/20 0.47
TACR1 P25103 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
NPC1 O15118 2/20 0.45
MAPT P10636 1/20 0.45
NLRP3 Q96P20 1/20 0.45
SLC6A2 P23975 1/20 0.45
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
SLC6A4 P31645 1/20 0.45
HTR7 P34969 1/20 0.45
HTR2B P41595 1/20 0.45
HTR3A P46098 1/20 0.45
SLC6A3 Q01959 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404861 0.92 TACR1 (0.48) CYP1A2SLC1A3SLC1A2SLC1A1CYP2A6
SCHEMBL28936085 0.91 CYP1A2 (0.54) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL6443296 0.87 SLC1A3 (0.51) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL6443298 0.87 SLC1A3 (0.55) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL18499920 0.87 CYP1A2 (0.46) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL2619047 0.87 TACR1 (0.47) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL29503697 0.87 TACR1 (0.47) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL6406854 0.85 SLC1A3 (0.50) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL487508 0.85 ALDH1A1 (0.61) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A
SCHEMBL30924172 0.85 SLC1A3 (0.54) CYP1A2SLC1A3SLC1A2SLC1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181122-A Benzyl thioether compound and preparation method thereof 苏州照固新材料科技有限公司 2022-03-15 CN claimed
CN-114181122-A Benzyl thioether compound and preparation method thereof 苏州照固新材料科技有限公司 2022-03-15 CN disclosed