SCHEMBL6910671

SCHEMBL6910671

CC(C)OC(=O)N(C(=O)[C@@H](N)C(C)C)C(c1nc2cc(Cl)ccc2s1)C(C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 8/20 0.43
AKR1B1 P15121 1/20 0.38
HDAC6 Q9UBN7 1/20 0.36
ALOX5 P09917 3/20 0.35
SENP7 Q9BQF6 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AGPAT2 O15120 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
IDO1 P14902 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910037 0.86 ALOX5 (0.45) AKR1B1ALOX5SENP7CYP1A2CYP2C9
SCHEMBL6905273 0.84 AKR1B1 (0.41) PPARAAKR1B1HDAC6ALOX5SENP7
SCHEMBL6910902 0.81 SENP7 (0.38) PPARAAKR1B1HDAC6ALOX5SENP7
SCHEMBL7478255 0.81 SENP7 (0.38) PPARAAKR1B1HDAC6ALOX5SENP7
SCHEMBL7479002 0.81 SENP7 (0.38) PPARAAKR1B1HDAC6ALOX5SENP7
SCHEMBL5970175 0.78 MEN1 (0.36) PPARACYP2D6CYP2C9CYP2C19MEN1
SCHEMBL6910367 0.78 MEN1 (0.36) PPARACYP2D6CYP2C9CYP2C19MEN1
SCHEMBL6905748 0.78 MEN1 (0.36) PPARACYP2D6CYP2C9CYP2C19MEN1
SCHEMBL6912541 0.72 ALOX5 (0.35) ALOX5CYP2C19
SCHEMBL6912020 0.70 PKM (0.45) AKR1B1ALOX5CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028125-B1 Dipeptide compounds having fungicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2004-01-28 EP claimed