Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455380 | 0.86 | ALDH1A1 (0.32) | ALDH1A1BCHEACHEMEN1CYP1A2 | |
| SCHEMBL6904355 | 0.81 | PDK2 (0.33) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL6749222 | 0.80 | PDK2 (0.32) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL6908963 | 0.77 | HTT (0.36) | ALDH1A1MAPTACHEMEN1CYP1A2 | |
| SCHEMBL27454709 | 0.75 | ACHE (0.37) | MAPTACHESMN1; SMN2 | |
| SCHEMBL27455379 | 0.68 | APAF1 (0.43) | APAF1TDP2NSD2HKDC1HSD11B1 | |
| SCHEMBL6912076 | 0.68 | BCHE (0.38) | APAF1TDP2NSD2HKDC1HSD11B1 | |
| SCHEMBL6525880 | 0.67 | BCHE (0.38) | APAF1TDP2NSD2HKDC1HSD11B1 | |
| SCHEMBL6911052 | 0.64 | BCHE (0.37) | APAF1HSD11B1ALDH1A1MAPTOPRK1 | |
| SCHEMBL7034169 | 0.63 | MAPT (0.36) | ALDH1A1MAPTACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| CN-1114609-C | 3-heteroatom substituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-07-16 | — | — | CN | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| CN-1230190-A | 3-heteroatom sustituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | CN | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |