Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904355 | 0.99 | PDK2 (0.33) | PDK2APAF1TDP2NSD2HKDC1 | |
| SCHEMBL7034169 | 0.82 | MAPT (0.36) | ALDH1A1MAPT | |
| SCHEMBL6908963 | 0.80 | HTT (0.36) | ALDH1A1MAPT | |
| SCHEMBL6911049 | 0.80 | APAF1 (0.32) | PDK2APAF1TDP2NSD2HKDC1 | |
| SCHEMBL27454709 | 0.78 | ACHE (0.37) | MAPT | |
| SCHEMBL6908340 | 0.74 | PDK2 (0.32) | PDK2 | |
| SCHEMBL6909658 | 0.74 | PDK2 (0.31) | PDK2 | |
| SCHEMBL6909966 | 0.69 | LMNA (0.33) | APAF1ALDH1A1MAPT | |
| SCHEMBL6910204 | 0.67 | APAF1 (0.33) | PDK2APAF1ALDH1A1MAPT | |
| SCHEMBL27455380 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004044018-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-05-27 | — | — | WO | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |