SCHEMBL6911056

SCHEMBL6911056

Fc1ccc([B-](c2ccc(F)cc2)(c2ccc(F)cc2)c2ccc(F)cc2)cc1.c1ccc([PH+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.37
PTGS1 P23219 1/20 0.34
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20841979 0.84 NFE2L2 (0.44) NFE2L2PTGS1MAPTNPC1
SCHEMBL335967 0.84 ALDH1A1 (0.35)
SCHEMBL6913920 0.81 CYP1A2 (0.32) NFE2L2
Biphenyl SCHEMBL4385685 0.79 ALDH1A1 (0.45) MAPTMAPK1HTTNPC1
SCHEMBL6909896 0.78 LMNA (0.42) MAPTHTTNPSR1L3MBTL1NPC1
Tetraphenylphosphonium SCHEMBL2498600 0.78 NFE2L2 (0.37) NFE2L2PTGS1MAPTMAPK1HTT
SCHEMBL689497 0.78 CA1 (0.42) NFE2L2NPC1
SCHEMBL6911272 0.78 NFE2L2 (0.38) NFE2L2MAPK1NPC1
Aniline SCHEMBL8720081 0.76 NFE2L2 (0.38) NFE2L2PTGS1MAPTNPC1
SCHEMBL623289 0.75 CA1 (0.40) NFE2L2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969010-B1 Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO LTD (JP) 2004-09-22 EP disclosed
US-6352953-B1 TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN JAPAN POLYOLEFINS CO., LTD. (JP) 2002-03-05 US disclosed
US-6150544-A Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO., LTD. (JP) 2000-11-21 US disclosed
EP-0969010-A2 Transition metal compound and catalyst containing the same for polymerization of olefins Japan Polyolefins Co., Ltd. (JP) 2000-01-05 EP disclosed
EP-0714920-B1 Catalyst for polymerization of olefins NIPPON OIL CO LTD (JP) 1997-11-05 EP disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0714920-A1 Catalyst for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1996-06-05 EP disclosed