SCHEMBL6911088

SCHEMBL6911088

C=[Zr](C1=Cc2ccccc2C1C)C1=Cc2ccccc2C1C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.37
DRD4 P21917 5/20 0.37
BRD4 O60885 1/20 0.36
CCL2 P13500 1/20 0.36
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL6513380 0.96 DRD2 (0.36) DRD2DRD4BRD4CCL2
SCHEMBL30387291 0.82 DRD2 (0.38) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL27547600 0.80 DRD2 (0.37) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL3743757 0.77 DRD2 (0.36) DRD2DRD4BRD4CCL2
SCHEMBL3745479 0.77 DRD2 (0.36) DRD2DRD4BRD4CCL2
SCHEMBL6910382 0.76
SCHEMBL6913883 0.76
SCHEMBL6912880 0.73 LMNA (0.35)
SCHEMBL29458545 0.70 DRD2 (0.41) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL251288 0.70 DRD2 (0.41) DRD2DRD4BRD4CCL2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6693156-B1 SIMPLY AND EFFICIENTLY SYNTHESIZED MATERIALS WITH VARIED SUBSTITUTION FOR TAILORED POLYMER PROPERTIES BASELL POLYOLEFINE GMBH (DE) 2004-02-17 US disclosed
US-6541584-B1 Homo or copolymerizing one or more olefinic monomer in presence of a bis/tetrahydroindenyl/ metallocene catalyst BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-04-01 US disclosed