SCHEMBL3743757

SCHEMBL3743757

CC1C([Zr](C2=Cc3ccccc3C2C)[SiH](C)C)=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.36
DRD4 P21917 5/20 0.36
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30387291 0.79 DRD2 (0.38) DRD2DRD4BRD4CCL2
SCHEMBL6911088 0.77 DRD2 (0.37) DRD2DRD4BRD4CCL2
SCHEMBL27547600 0.77 DRD2 (0.37) DRD2DRD4BRD4CCL2
SCHEMBL3745479 0.74 DRD2 (0.36) DRD2DRD4BRD4CCL2
Chloromethane SCHEMBL6513380 0.74 DRD2 (0.36) DRD2DRD4BRD4CCL2
SCHEMBL251288 0.67 DRD2 (0.41) DRD2DRD4BRD4CCL2
SCHEMBL29458545 0.67 DRD2 (0.41) DRD2DRD4BRD4CCL2
Lithium SCHEMBL9145416 0.66 DRD2 (0.40) DRD2DRD4BRD4CCL2
SCHEMBL5475152 0.66 DRD2 (0.40) DRD2DRD4BRD4CCL2
SCHEMBL9148116 0.66 DRD2 (0.40) DRD2DRD4BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds MUC1, OPRD1, CEL DRD2 1401/4885DRD4 1513/4885BRD4 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.