Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911088 | 0.73 | DRD2 (0.37) | — | |
| SCHEMBL29115214 | 0.72 | ALDH1A1 (0.33) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL15661815 | 0.71 | HDAC4 (0.38) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL6673270 | 0.71 | GAA (0.35) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL29213168 | 0.71 | LMNA (0.34) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL3205637 | 0.71 | LMNA (0.34) | LMNATP53CYP1A2CYP3A4MAPT | |
| Chloromethane SCHEMBL6513380 | 0.70 | DRD2 (0.36) | — | |
| SCHEMBL6905400 | 0.70 | — | — | |
| SCHEMBL1387828 | 0.69 | CFTR (0.38) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL7191962 | 0.69 | LMNA (0.33) | LMNATP53CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693156-B1 | SIMPLY AND EFFICIENTLY SYNTHESIZED MATERIALS WITH VARIED SUBSTITUTION FOR TAILORED POLYMER PROPERTIES | BASELL POLYOLEFINE GMBH (DE) | 2004-02-17 | — | — | US | disclosed |