SCHEMBL6911166

SCHEMBL6911166

CCc1c(N)c(SC)cc(SC)c1N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803884 0.87 ALDH1A1 (0.35) NOS3NOS2
SCHEMBL19988216 0.87 HTT (0.37)
SCHEMBL8764984 0.87 KMT2A (0.33)
SCHEMBL28989150 0.79
SCHEMBL6910764 0.79 AOC3 (0.39)
SCHEMBL6914527 0.79 SKP2 (0.39) NOS2
SCHEMBL8536715 0.76 NPC1 (0.33) NOS3NOS2
SCHEMBL48437 0.72 ALDH1A1 (0.33)
SCHEMBL9578834 0.72
SCHEMBL10885370 0.71 GABRA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1265940-B1 AROMATIC AMINE CURATIVES AND THEIR USE ALBERMARLE CORP (US) 2004-10-27 EP disclosed
US-6509434-B1 Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas ALBEMARLE CORPORATION 2003-01-21 US disclosed
EP-1265940-A2 AROMATIC AMINE CURATIVES AND THEIR USE Albermarle Corporation (US) 2002-12-18 EP disclosed
WO-2001070841-A2 AROMATIC AMINE CURATIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2001-09-27 WO disclosed
US-5393806-A Adding a curing accelerator composition containing a mixture of a boron halide and an imidazole ALBEMARLE CORPORATION (US) 1995-02-28 US disclosed