Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060663 | 0.77 | NOS3 (0.37) | MEN1KMT2ANOS3NOS2ALDH1A1 | |
| SCHEMBL11127368 | 0.76 | DHFR (0.40) | ALDH1A1MAPT | |
| SCHEMBL6911166 | 0.76 | NOS3 (0.30) | NOS3NOS2 | |
| SCHEMBL30117633 | 0.74 | NOS3 (0.41) | NPC1MEN1KMT2AAPOBEC3GNOS3 | |
| SCHEMBL215981 | 0.74 | NOS3 (0.41) | NPC1MEN1KMT2AAPOBEC3GNOS3 | |
| Hydrochloric Acid SCHEMBL9640854 | 0.71 | NOS3 (0.39) | NPC1MEN1KMT2AAPOBEC3GNOS3 | |
| Hydrochloric Acid SCHEMBL4662390 | 0.71 | NOS3 (0.39) | NPC1MEN1KMT2AAPOBEC3GNOS3 | |
| SCHEMBL459542 | 0.71 | POLB (0.38) | NOS3NOS2ALDH1A1POLBMAPT | |
| SCHEMBL29430589 | 0.71 | POLB (0.38) | NOS3NOS2ALDH1A1POLBMAPT | |
| SCHEMBL30324471 | 0.71 | NOS3 (0.42) | MEN1KMT2ANOS3NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | claimed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | disclosed |
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |