SCHEMBL6911352

SCHEMBL6911352

CC(=O)NS(=O)(=O)c1cccc(CCC(=O)N[C@@](C)(Cc2ccc([N+](=O)[O-])cc2)C(N)=O)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.38
MMP1 P03956 5/20 0.38
MMP2 P08253 5/20 0.38
MMP9 P14780 5/20 0.38
MMP8 P22894 5/20 0.38
MMP13 P45452 5/20 0.38
CYP19A1 P11511 2/20 0.37
KDM1A O60341 2/20 0.37
MAOA P21397 2/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
FAAH O00519 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ALOX5 P09917 1/20 0.36
TRPV1 Q8NER1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911344 0.77 L3MBTL1 (0.41) L3MBTL1POLBMMP1MMP2MMP9
SCHEMBL6911343 0.76 L3MBTL1 (0.45) L3MBTL1MMP1MMP2MMP9MMP8
SCHEMBL6911348 0.76 L3MBTL1 (0.45) L3MBTL1MMP1MMP2MMP9MMP8
SCHEMBL6925851 0.73 ALDH1A1 (0.48) L3MBTL1MMP1MMP2MMP9MMP8
SCHEMBL6926341 0.71 KMT2A (0.48) MMP1MMP2MMP9MMP8MMP13
SCHEMBL6397464 0.69 L3MBTL1 (0.55) L3MBTL1ALDH1A1
SCHEMBL8548451 0.69 CA2 (0.68) MMP1MMP2MMP9MMP8MMP13
SCHEMBL7211717 0.68 KMT2A (0.63) MMP1MMP2MMP9MMP8MMP13
SCHEMBL23703023 0.68 ALDH1A1 (0.61) L3MBTL1MMP1MMP2MMP9MMP8
SCHEMBL6912845 0.66 GAA (0.52) L3MBTL1POLBLMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE L3MBTL1 3997/4885POLB 3615/4885MMP1 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.