Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773236 | 0.75 | CYP2C9 (0.50) | CYP2D6PKMCYP2C9MMP2PARL | |
| SCHEMBL4551501 | 0.68 | SRC (0.46) | CYP2D6PKMCYP2C9MMP2PARL | |
| (Phenylsulfonyl)Benzene SCHEMBL8958296 | 0.66 | HTR6 (0.74) | MMP2CA12CA1CA2CA3 | |
| (Phenylsulfonyl)Benzene SCHEMBL28297601 | 0.66 | HTR6 (0.74) | MMP2CA12CA1CA2CA3 | |
| Carbamic Acid SCHEMBL28801958 | 0.65 | TSHR (0.80) | CYP2D6MMP2CYP3A4CYP2C19CA12 | |
| Benzenesulfonamide SCHEMBL27896159 | 0.65 | CA2 (0.80) | CYP2C19CA12CA1CA2CA3 | |
| Benzenesulfonamide SCHEMBL3971272 | 0.65 | CA2 (0.80) | CYP2C19CA12CA1CA2CA3 | |
| Benzenesulfonamide SCHEMBL19348104 | 0.65 | CA2 (0.80) | CYP2C19CA12CA1CA2CA3 | |
| Urea SCHEMBL7500665 | 0.65 | TSHR (0.80) | CYP2D6MMP2CYP3A4CYP2C19CA12 | |
| SCHEMBL1526740 | 0.65 | SMN1; SMN2 (0.50) | MMP2CYP3A4CYP2C19CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767931-B2 | POLYDIORGANOSILOXANE; FOOTWEAR; WEAR RESISTANCE | DOW GLOBAL TECHNOLOGIES INC. | 2004-07-27 | — | — | US | claimed |