Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 12/20 | 0.50 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401637 | 0.74 | QTRT1 (0.47) | TYMSQTRT1DHFR | |
| SCHEMBL28932180 | 0.72 | TYMS (0.56) | TYMSQTRT1DHFR | |
| SCHEMBL8873096 | 0.71 | QTRT1 (0.49) | TYMSQTRT1DHFR | |
| SCHEMBL8872977 | 0.69 | QTRT1 (0.49) | TYMSQTRT1DHFR | |
| SCHEMBL103994 | 0.69 | QTRT1 (1.00) | TYMSQTRT1TUBB4ATUBBTUBA3C | |
| SCHEMBL27812021 | 0.68 | TYMS (0.46) | TYMSQTRT1DHFR | |
| SCHEMBL6654365 | 0.68 | TYMS (1.00) | TYMSQTRT1 | |
| SCHEMBL30589037 | 0.68 | TYMS (1.00) | TYMSQTRT1 | |
| SCHEMBL28787846 | 0.68 | TYMS (0.54) | TYMSQTRT1DHFR | |
| SCHEMBL11250039 | 0.66 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012769-A1 | THERAPEUTIC INHIBITIONOF PROTEIN KINASES IN CANCER CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-02-12 | — | — | WO | claimed |