Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.56 |
| ▸ | ABCC8 | Q09428 | 12/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 12/20 | 0.56 |
| ▸ | KCNJ8 | Q15842 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910817 | 0.89 | ABCC9 (0.70) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6912871 | 0.87 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL6911320 | 0.77 | ABCC9 (0.62) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL6908699 | 0.72 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL3320454 | 0.63 | ALDH1A1 (0.65) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL3035270 | 0.63 | TSHR (0.59) | ALDH1A1HPGDHSD17B10NPSR1KDM4E | |
| SCHEMBL8437322 | 0.63 | NPSR1 (0.49) | LMNAHPGDHSD17B10NPSR1KDM4E | |
| SCHEMBL7239344 | 0.62 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8322694 | 0.62 | MAPT (0.35) | ALDH1A1LMNAHPGDNPSR1TSHR | |
| SCHEMBL6910783 | 0.61 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040097-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2004-04-14 | — | — | EP | claimed |