SCHEMBL6912864

SCHEMBL6912864

CS(=O)(=O)c1cc(O)nc(O)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ENPP2 Q13822 1/20 0.32
GLP1R P43220 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6806147 0.76 LMNA (0.53) LMNASMN1; SMN2
SCHEMBL19972822 0.75 ENPP2 (0.41) LMNASMN1; SMN2ENPP2GLP1R
SCHEMBL3599220 0.71 ENPP2 (0.33) ENPP2
SCHEMBL27519649 0.70 LMNA (0.50) LMNASMN1; SMN2ENPP2
SCHEMBL27318725 0.70 ENPP2 (0.32) ENPP2
SCHEMBL127131 0.69
SCHEMBL24156661 0.68 ENPP2 (0.35) LMNASMN1; SMN2ENPP2GLP1R
SCHEMBL3599060 0.68 ENPP2 (0.35) LMNAENPP2
SCHEMBL9626200 0.67 LMNA (0.52) LMNASMN1; SMN2GLP1R
SCHEMBL24773615 0.65 HSP90AA1 (0.43) LMNASMN1; SMN2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004075899-A1 A METHOD OF PREVENTION OF LYSOSOMAL LEAKAGE IN EUKARYOTIC CELLS BY USING 6-METHYLURACIL BASED WATER-SOLUBLE COMPOUNDS AND METHOD OF PRODUCING AND USE THEREOF TECHNOLOGY COMMERCCIALIZATION CORP. (US) 2004-09-10 WO claimed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP disclosed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP disclosed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO disclosed