Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058928 | 0.84 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL405156 | 0.76 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL2401353 | 0.76 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL70201 | 0.74 | ALDH1A1 (0.62) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL8902281 | 0.74 | ALDH1A1 (0.62) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL8580453 | 0.74 | ALDH1A1 (0.62) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL70202 | 0.74 | ALDH1A1 (0.62) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL20448823 | 0.73 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| Benzene SCHEMBL28103329 | 0.73 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E | |
| SCHEMBL29556927 | 0.73 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP1A2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689899-B2 | HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20020019558-A1 | Diamine and acid anhydride | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-14 | — | — | US | disclosed |
| US-6303742-B1 | CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. | KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019558-A1 | Diamine and acid anhydride | CA1, ASIC1, CA4 | ALDH1A1 116/4885ALOX15 3177/4885CYP1A2 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.