Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560065 | 0.74 | MAOA (0.56) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL6200206 | 0.74 | MAOA (0.57) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL10403751 | 0.74 | MAOA (0.47) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL10402449 | 0.74 | MAOA (0.47) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL10402868 | 0.74 | MAOA (0.57) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL7440144 | 0.71 | MAOA (0.52) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL10404334 | 0.70 | MTNR1A (0.50) | MAOAMAOBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL10402862 | 0.68 | CYP1A2 (0.44) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL2951869 | 0.68 | MTNR1A (0.51) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL26826115 | 0.68 | MAOA (0.53) | MAOAMAOBALDH1A1MAPK1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818423-B2 | LOW-MOLECULAR-WEIGHT C4-C6-KETONES DERIVATIZED WITH REMOVABLE GROUP ARE REACTED WITH CYANIDE GROUP DONOR IN PRESENCE OF HYDROXYNITRILE LYASE OR BY RACEMIC REACTION, ACIDIC HYDROLYSIS, OPTIONALLY RESOLUTION, AND CLEAVAGE OF THE GROUP | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) | 2004-11-16 | — | — | US | disclosed |
| US-20030092142-A1 | Process for the preparation of chiral alpha-hydroxycarboxylic acids | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2003-05-15 | — | — | US | disclosed |