Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915512 | 1.00 | SYNJ2 (0.41) | SYNJ2L3MBTL1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL4293687 | 0.75 | KDM4E (0.49) | SYNJ2L3MBTL1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL16620686 | 0.72 | SLC5A2 (0.40) | ALDH1A1SLC5A2PYGL | |
| SCHEMBL9293545 | 0.72 | SLC5A2 (0.40) | ALDH1A1SLC5A2PYGL | |
| SCHEMBL1022027 | 0.72 | SLC5A2 (0.40) | ALDH1A1SLC5A2PYGL | |
| SCHEMBL1998975 | 0.72 | SLC5A2 (0.40) | ALDH1A1SLC5A2PYGL | |
| SCHEMBL13317068 | 0.70 | SLC5A2 (0.57) | SLC5A2 | |
| SCHEMBL3786766 | 0.69 | SLC5A2 (0.47) | CYP1A2KDM4EALDH1A1MAPTSLC5A2 | |
| SCHEMBL1444855 | 0.69 | SLC5A2 (0.47) | CYP1A2KDM4EALDH1A1MAPTSLC5A2 | |
| SCHEMBL7024599 | 0.69 | SLC5A2 (0.47) | CYP1A2KDM4EALDH1A1MAPTSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122223-A1 | Non-natural nucleotides and dinucleotides | CELLTECH R & D LIMITED (GB) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122223-A1 | Non-natural nucleotides and dinucleotides | P2RY1, P2RY11, P2RY13 | SYNJ2 1378/4885L3MBTL1 4753/4885CYP1A2 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.