Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 4/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30531179 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL16620686 | 0.77 | SLC5A2 (0.40) | ALDH1A1SLC5A2PNP | |
| SCHEMBL9293545 | 0.77 | SLC5A2 (0.40) | ALDH1A1SLC5A2PNP | |
| SCHEMBL1998975 | 0.77 | SLC5A2 (0.40) | ALDH1A1SLC5A2PNP | |
| SCHEMBL1022027 | 0.77 | SLC5A2 (0.40) | ALDH1A1SLC5A2PNP | |
| SCHEMBL6915520 | 0.75 | SYNJ2 (0.41) | KDM4EALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL6915512 | 0.75 | SYNJ2 (0.41) | KDM4EALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL3786766 | 0.71 | SLC5A2 (0.47) | KDM4EALDH1A1CYP1A2MAPTSLC5A2 | |
| SCHEMBL1444855 | 0.71 | SLC5A2 (0.47) | KDM4EALDH1A1CYP1A2MAPTSLC5A2 | |
| SCHEMBL16620205 | 0.71 | UMPS (0.44) | KDM4ECYP1A2MAPTPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | MALLINCKRODT INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | EIF2AK2, MAVS, IRF3 | KDM4E 3033/4885ALDH1A1 3014/4885TDP1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.