Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212660 | 0.86 | KDM4E (0.41) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL4576511 | 0.83 | OPRD1 (0.59) | OPRD1 | |
| SCHEMBL4591245 | 0.81 | CYP3A4 (0.54) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8009424 | 0.81 | CYP3A4 (0.54) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL7993545 | 0.81 | CYP3A4 (0.54) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8009013 | 0.78 | OPRD1 (0.34) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8004080 | 0.78 | OPRD1 (0.34) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8002904 | 0.78 | OPRD1 (0.34) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8160003 | 0.74 | OPRD1 (0.41) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL8930486 | 0.73 | OPRD1 (0.55) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057223-A9 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS INC (US) | 2004-04-29 | — | — | WO | disclosed |