Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820925 | 0.81 | BCL2 (0.40) | KDM4ERCE1ALDH1A1MEN1KMT2A | |
| SCHEMBL6820233 | 0.80 | CYP19A1 (0.59) | KDM4ERCE1ALDH1A1MEN1KMT2A | |
| SCHEMBL29093697 | 0.78 | CYP19A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL30616072 | 0.78 | CYP19A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL29244218 | 0.74 | TSPO (0.48) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL31022839 | 0.74 | TSPO (0.48) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL24642212 | 0.74 | L3MBTL1 (0.41) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL15823716 | 0.72 | TSPO (0.42) | FEN1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL23131640 | 0.71 | ABCB1 (0.39) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8245792 | 0.71 | EGLN1 (0.76) | KDM4EMEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |