Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820714 | 0.85 | THRB (0.39) | BCL2MCL1KDM4ERCE1ALDH1A1 | |
| SCHEMBL6915948 | 0.81 | KDM4E (0.43) | KDM4ERCE1GAAALDH1A1POLB | |
| SCHEMBL6424798 | 0.74 | ACLY (0.45) | MCL1AGTR1CYP2C19HSD17B10KMT2A | |
| SCHEMBL6820233 | 0.72 | CYP19A1 (0.59) | KDM4ERCE1GAAALDH1A1POLB | |
| SCHEMBL10179380 | 0.68 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTRORARORC | |
| SCHEMBL12591789 | 0.66 | GAA (0.41) | GAAALDH1A1LMNAHTTNPC1 | |
| SCHEMBL6920117 | 0.65 | CA12 (0.48) | KDM4EGAAALDH1A1CYP2C19MAPT | |
| SCHEMBL15832276 | 0.64 | TSPO (0.42) | PTGES2ALDH1A1KMT2ALMNA | |
| SCHEMBL6821169 | 0.63 | KMT2A (0.52) | KDM4EGAAALDH1A1POLBHPGD | |
| SCHEMBL6422478 | 0.63 | ACLY (0.41) | MCL1KDM4EGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |