Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918963 | 0.83 | KDR (0.50) | CYP19A1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6821169 | 0.82 | KMT2A (0.52) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6821059 | 0.82 | MAPT (0.48) | CYP19A1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6920117 | 0.82 | CA12 (0.48) | CYP19A1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6915948 | 0.80 | KDM4E (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27959994 | 0.80 | CYP19A1 (0.59) | CYP19A1P2RX4MEN1KMT2AKDM4E | |
| SCHEMBL9685003 | 0.80 | CYP19A1 (0.54) | CYP19A1P2RX4MEN1KMT2AKDM4E | |
| SCHEMBL6821058 | 0.79 | PLA2G2A (0.57) | KMT2AMAPTMAPK1NTRK1 | |
| SCHEMBL9584036 | 0.79 | CYP19A1 (0.58) | CYP19A1P2RX4MEN1KMT2AKDM4E | |
| SCHEMBL28712753 | 0.77 | ALDH1A1 (0.59) | CYP19A1P2RX4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |