SCHEMBL6916208

SCHEMBL6916208

O=S(=O)(Oc1ccccc1)c1cccc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
HTR6 P50406 2/20 0.52
ALDH1A1 P00352 5/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 3/20 0.47
THRB P10828 1/20 0.47
TSHR P16473 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAOB P27338 1/20 0.45
CA2 P00918 3/20 0.44
CA1 P00915 1/20 0.44
CA9 Q16790 1/20 0.44
HTT P42858 2/20 0.43
F2 P00734 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 2/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL9579914 0.88 TDP1 (0.66) TDP1HTR6ALDH1A1SMN1; SMN2NPSR1
SCHEMBL9333331 0.82 TDP1 (0.69) TDP1HTR6ALDH1A1SMN1; SMN2LMNA
SCHEMBL19146 0.82 TDP1 (0.73) TDP1HTR6ALDH1A1SMN1; SMN2MAOB
SCHEMBL7981247 0.82 TDP1 (0.73) TDP1HTR6ALDH1A1SMN1; SMN2MAOB
SCHEMBL28709181 0.82 HTR6 (0.78) TDP1HTR6ALDH1A1SMN1; SMN2LMNA
SCHEMBL9140147 0.82 HTR6 (0.78) TDP1HTR6ALDH1A1SMN1; SMN2LMNA
SCHEMBL11847020 0.81 CA2 (0.60) TDP1ALDH1A1SMN1; SMN2LMNANPSR1
SCHEMBL4429067 0.80 F2 (0.56) TDP1HTR6ALDH1A1SMN1; SMN2MAOB
SCHEMBL9116912 0.80 LMNA (0.55) TDP1HTR6ALDH1A1SMN1; SMN2LMNA
SCHEMBL196783 0.80 TDP1 (0.66) TDP1ALDH1A1SMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed