SCHEMBL6916267

SCHEMBL6916267

CCCCCN(C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](Cc1ccc(Nc2ccccc2)cc1)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.46
ACE P12821 1/20 0.45
REN P00797 2/20 0.45
CTSS P25774 2/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
PTPN1 P18031 2/20 0.43
PTPRA P18433 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830642 0.91 CTSK (0.47) CTSKACERENCTSSCTSL
SCHEMBL6796549 0.87 PPARG (0.45) CTSKCTSSCTSLCTSBPTPN1
SCHEMBL6916264 0.83 REN (0.45) CTSKACERENCTSSCTSL
SCHEMBL9438871 0.81 CTSK (0.57) CTSKACECTSSCTSLCTSB
SCHEMBL6796546 0.79 REN (0.45) CTSKACERENCTSSCTSL
SCHEMBL7064449 0.78 CTSK (0.43) CTSK
SCHEMBL7572392 0.78 PTPN1 (0.70) PTPN1PTPRA
SCHEMBL6916272 0.77 PTPN1 (0.68) CTSKCTSSCTSLCTSBPTPN1
SCHEMBL9439254 0.76 BCL2 (0.56) CTSKRENPTPN1
SCHEMBL7618822 0.76 REN (0.67) CTSKACERENCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE CTSK 2457/4885ACE 858/4885REN 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.