SCHEMBL6916428

SCHEMBL6916428

COC(=Cc1ccccc1)C(Cl)=Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
NFKB1 P19838 3/20 0.51
NFKB2 Q00653 3/20 0.51
RELA Q04206 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 4/20 0.46
MEN1 O00255 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
ALDH1A1 P00352 2/20 0.46
ABCG2 Q9UNQ0 1/20 0.45
LMNA P02545 1/20 0.43
FBP1 P09467 2/20 0.40
TSHR P16473 1/20 0.39
AKR1C3 P42330 1/20 0.39
KDM1A O60341 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1569429 0.82 ABCG2 (0.51) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL7072648 0.82 ABCG2 (0.51) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL7068438 0.82 ABCG2 (0.51) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL11243856 0.79 ABCG2 (0.47) KMT2AMEN1ALDH1A1ABCG2FBP1
SCHEMBL6151503 0.79 ABCG2 (0.47) KMT2AMEN1ALDH1A1ABCG2FBP1
SCHEMBL10500027 0.79 FBP1 (0.45) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL5707178 0.78 RAB9A (0.53) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL9486859 0.78 RAB9A (0.53) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL10625694 0.78 RAB9A (0.53) RAB9AKMT2ANPC1SMN1; SMN2NFKB1
SCHEMBL15152887 0.78 ABCG2 (0.48) RAB9AKMT2ANPC1SMN1; SMN2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828086-B2 For use in imaging material KONICA CORPORATION (JP) 2004-12-07 US disclosed
US-20030186180-A1 Water-based coating composition, infrared absorbing film, and photothermographic material by use thereof KONICA CORPORATION (JP) 2003-10-02 US disclosed
EP-0439072-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-31 EP disclosed