Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359907 | 0.76 | FFAR1 (0.41) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL11767314 | 0.74 | HPGD (0.41) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| Fluoride SCHEMBL11728897 | 0.73 | HPGD (0.39) | FFAR1ALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL4654046 | 0.73 | NPSR1 (0.43) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL7078994 | 0.71 | CYP3A4 (0.43) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL4522173 | 0.71 | ALDH1A1 (0.38) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL31319056 | 0.70 | SMN1; SMN2 (0.44) | FFAR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL7079000 | 0.70 | CYP3A4 (0.46) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL19664731 | 0.70 | HPGD (0.45) | FFAR1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL4558248 | 0.70 | SIRT1 (0.42) | FFAR1ALDH1A1HPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686391-B2 | N-(MONO-, DI- TRICHLOROPHENYL)CARBAMATES, THIOCARBAMATES OR DITHIOCARBAMATES; ANTICARCINOGENIC AGENTS; VIRICIDES; SAFER THAN ADRIAMYCIN ON HEALTHY CELLS; EFFECTIVE AGAINST CELLS OF MONCYTIC LINAGE INFECTED WITH HIV | UNIVERSITY OF ARIZONA FOUNDATION | 2004-02-03 | — | — | US | disclosed |
| US-6498188-B1 | ADMINISTRATING AN N-CHLOROPHENYLCARBAMATE OR AN N-CHLORO-PHENYLTHIOCARBAMATE IN COMBINATION WITH POTENTIATOR AND/OR CHEMOTHERAPEUTIC AGENT | THE PROCTER & GAMBLE COMPANY | 2002-12-24 | — | — | US | disclosed |
| US-20010002403-A1 | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions | THE PROCTER & GAMBLE COMPANY | 2001-05-31 | — | — | US | disclosed |
| EP-0820282-A1 | A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5656615-A | Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1996032103-A1 | A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010002403-A1 | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions | TP53, CPS1, MGMT | FFAR1 4780/4885ALDH1A1 2801/4885HPGD 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.