Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767314 | 0.83 | HPGD (0.41) | ALDH1A1HPGDFFAR1RAB9ANPC1 | |
| SCHEMBL11760405 | 0.82 | SCN2A (0.39) | ALDH1A1HPGDTSHRSMN1; SMN2SCN2A | |
| Fluoride SCHEMBL11728897 | 0.81 | HPGD (0.39) | ALDH1A1HPGDFFAR1RAB9ANPC1 | |
| SCHEMBL11680470 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL2981447 | 0.79 | SCN2A (0.40) | ALDH1A1HPGDFFAR1TSHRRAB9A | |
| SCHEMBL11092905 | 0.79 | HPGD (0.38) | ALDH1A1HPGDFFAR1RAB9ANPC1 | |
| SCHEMBL11528680 | 0.76 | LMNA (0.42) | ALDH1A1HPGDFFAR1RAB9ANPC1 | |
| SCHEMBL6916757 | 0.71 | FFAR1 (0.41) | ALDH1A1HPGDFFAR1TSHRRAB9A | |
| SCHEMBL18499751 | 0.70 | MGLL (0.41) | ALDH1A1HPGDFFAR1TSHRSMN1; SMN2 | |
| SCHEMBL19664731 | 0.70 | HPGD (0.45) | ALDH1A1HPGDFFAR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| EP-0009324-A1 | Substituted 1-benzoyl-3-thiosemicarbazides, their manufacture and use as plant growth regulants, and agricultural formulations comprising them | Gulf Oil Corporation (US) | 1980-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | IL4, IL4I1, IL2 | ALDH1A1 1406/4885HPGD 83/4885FFAR1 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.