Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037693 | 0.81 | TEAD1 (0.43) | CYP2C9CYP2C19HSD17B10TSHRALDH1A1 | |
| SCHEMBL27345973 | 0.81 | NPC1 (0.50) | CYP2C9CYP2C19HSD17B10ALOX15TSHR | |
| SCHEMBL11768134 | 0.80 | ALDH1A1 (0.44) | CYP2C9CYP2C19ALDH1A1MAPTNPC1 | |
| SCHEMBL5178134 | 0.79 | FFAR1 (0.43) | CYP2C19HSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL27517395 | 0.79 | NPC1 (0.48) | CYP2C9CYP2C19HSD17B10ALOX15TSHR | |
| SCHEMBL11409862 | 0.78 | ALDH1A1 (0.53) | CYP2C9CYP2C19HSD17B10ALOX15TSHR | |
| SCHEMBL7613932 | 0.74 | MAPK1 (0.53) | CYP2C9CYP2C19TSHRALDH1A1KDM4E | |
| SCHEMBL11064787 | 0.73 | LMNA (0.48) | HSD17B10ALOX15TSHRALDH1A1KDM4E | |
| 4-Chloro-Benzoic Acid SCHEMBL9470021 | 0.71 | TSHR (0.55) | CYP2C9HSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL11571322 | 0.71 | CYP2C19 (0.50) | CYP2C9CYP2C19HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686391-B2 | N-(MONO-, DI- TRICHLOROPHENYL)CARBAMATES, THIOCARBAMATES OR DITHIOCARBAMATES; ANTICARCINOGENIC AGENTS; VIRICIDES; SAFER THAN ADRIAMYCIN ON HEALTHY CELLS; EFFECTIVE AGAINST CELLS OF MONCYTIC LINAGE INFECTED WITH HIV | UNIVERSITY OF ARIZONA FOUNDATION | 2004-02-03 | — | — | US | disclosed |
| US-6498188-B1 | ADMINISTRATING AN N-CHLOROPHENYLCARBAMATE OR AN N-CHLORO-PHENYLTHIOCARBAMATE IN COMBINATION WITH POTENTIATOR AND/OR CHEMOTHERAPEUTIC AGENT | THE PROCTER & GAMBLE COMPANY | 2002-12-24 | — | — | US | disclosed |
| US-20010002403-A1 | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions | THE PROCTER & GAMBLE COMPANY | 2001-05-31 | — | — | US | disclosed |
| EP-0820282-A1 | A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5656615-A | Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1996032103-A1 | A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010002403-A1 | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions | TP53, CPS1, MGMT | CYP2C9 2694/4885CYP2C19 3246/4885HSD17B10 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.