Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050841 | 0.76 | TSHR (0.64) | ALDH1A1SMN1; SMN2MAPTNPC1ALOX15 | |
| SCHEMBL6916759 | 0.73 | CYP2C9 (0.48) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL11554950 | 0.71 | PKM (0.53) | LMNAL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28037693 | 0.71 | TEAD1 (0.43) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12311615 | 0.70 | KMT2A (0.64) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4725871 | 0.70 | MLYCD (0.47) | LMNAL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5933195 | 0.70 | ALDH1A1 (0.49) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5049977 | 0.70 | ROCK2 (0.51) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL137254 | 0.69 | LMNA (0.59) | LMNAL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8946061 | 0.69 | LMNA (0.59) | LMNAL3MBTL1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |