Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699992 | 0.88 | POLB (0.47) | MMP9MMP1MMP2MMP12GAA | |
| SCHEMBL8983017 | 0.86 | HTR1A (0.48) | HTR1AADRA1DADRA1AADRA1BGAA | |
| SCHEMBL691628 | 0.86 | RAB9A (0.55) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL21022925 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL29838082 | 0.84 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL9359762 | 0.82 | POLB (0.45) | MMP9MMP1MMP2MMP12GAA | |
| SCHEMBL9356233 | 0.81 | MAOB (0.48) | GAANPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL30849274 | 0.78 | PARP1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1ABCB1 | |
| SCHEMBL1305662 | 0.78 | HPGD (0.57) | GAANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1097626 | 0.78 | PPIA (0.48) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125950-B2 | Siderophore conjugate immunogenic compositions and vaccines | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150071961-A1 | SIDEROPHORE CONJUGATE IMMUNOGENIC COMPOSITIONS AND VACCINES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8834890-B2 | Siderophore conjugate immunogenic compositions and vaccines | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2557082-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | Shionogi & Co., Ltd. (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-20120052087-A1 | Siderophore Conjugate Immunogenic Compositions and Vaccines | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2421529-A2 | SIDEROPHORE CONJUGATE IMMUNOGENIC COMPOSITIONS AND VACCINES | University of Florida Research Foundation, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123845-A2 | SIDEROPHORE CONJUGATE IMMUNOGENIC COMPOSITIONS AND VACCINES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-10-28 | — | — | WO | disclosed |