Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356233 | 0.92 | MAOB (0.48) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL9359762 | 0.88 | POLB (0.45) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL691784 | 0.88 | MMP9 (0.51) | POLBNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL14882531 | 0.86 | SMN1; SMN2 (0.49) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL9356673 | 0.86 | RAB9A (0.56) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL18499402 | 0.83 | ALDH1A1 (0.55) | POLBRAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14699947 | 0.82 | NPC1 (0.55) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL14699870 | 0.80 | FFAR4 (0.46) | POLBNPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL27967578 | 0.80 | PKM (0.58) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23512705 | 0.79 | FFAR4 (0.51) | POLBNPC1RAB9ASMN1; SMN2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2557082-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | Shionogi & Co., Ltd. (JP) | 2013-02-13 | — | — | EP | disclosed |