Butane

Butane

SCHEMBL6918003

CCCC.C[SiH](C)[Zr](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474419 0.93 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL144110 0.93 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4ELMNA
Hydrochloric Acid SCHEMBL5839045 0.91 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Hydrochloric Acid SCHEMBL60271 0.91 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Methane SCHEMBL5838214 0.91 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Chloromethane SCHEMBL3682989 0.90 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Bromide SCHEMBL6910226 0.90 KDM4E (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL1617737 0.86 SIGMAR1 (0.38) HTR2AHTR6SIGMAR1KCNH2
(Chloromethyl)Benzene SCHEMBL7040024 0.83 SIGMAR1 (0.36) HTR2AHTR6SIGMAR1
SCHEMBL6062291 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed