SCHEMBL144110

SCHEMBL144110

C[SiH](C)[Zr](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474419 1.00 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL5839045 0.98 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Methane SCHEMBL5838214 0.98 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL60271 0.98 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Chloromethane SCHEMBL3682989 0.96 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Bromide SCHEMBL6910226 0.96 KDM4E (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Butane SCHEMBL6918003 0.93 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL1617737 0.89 SIGMAR1 (0.38) HTR2AHTR6SIGMAR1KCNH2
SCHEMBL6917289 0.87 GPR3 (0.31) HTR2AKDM4EBRD4CCL2LMNA
(Chloromethyl)Benzene SCHEMBL7040024 0.86 SIGMAR1 (0.36) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-20 US claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US claimed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US claimed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP claimed
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US claimed
US-20220289879-A1 Polymers of 4-Substituted Hexadiene and Processes for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-09-15 US claimed
EP-3559058-A1 SPRAY-DRIED OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND POLYMERIZATION PROCESSES FOR USING THE SAME ExxonMobil Chemical Patents Inc. (US) 2019-10-30 EP claimed
WO-2018118259-A1 SPRAY-DRIED OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND POLYMERIZATION PROCESSES FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-06-28 WO claimed
EP-2822975-B1 POLYOLEFIN ADHESIVE COMPOSITIONS AND METHODS OF PREPARING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-04-25 EP claimed
EP-2460834-B1 Improved acidic activator-supports and catalysts for olefin polymerization CHEVRON PHILLIPS CHEMICAL CO (US) 2015-08-12 EP claimed
EP-0824554-B1 AMORPHOUS OLEFIN CO/TER-POLYMERS OPTATECH CORP (FI) 2000-03-01 EP claimed
EP-0523416-B1 Catalyst and process for preparing high molecular weight polyolefines TARGOR GMBH (DE) 1999-10-20 EP claimed
EP-0822938-B1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORP (US) 1999-06-16 EP claimed
EP-0336128-B2 Process for preparing an alpha-olefin polymer TARGOR GMBH (DE) 1998-11-18 EP claimed
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0574597-B1 Process for the preparation of bridged, chiral metallocene catalysts of the bisindenyl type HOECHST AG (DE) 1998-01-21 EP claimed
EP-0798315-B1 Process for preparing highly active, stable metallocene catalyst systems, and catalyst compositions prepared according therewith WITCO GMBH (DE) 1997-10-29 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
EP-0284708-B1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY (US) 1996-01-31 EP claimed
EP-0384171-B1 Catalysts for the polymerization of olefins. AUSIMONT SRL (IT) 1993-05-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes LEF1, TAF1, FLI1 HTR2A 3365/4885HTR6 4173/4885SIGMAR1 880/4885
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes AS3MT, AP1M1, AP3M1 HTR2A 4311/4885HTR6 4581/4885SIGMAR1 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.