Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | NQO2 | P16083 | 7/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740691 | 0.87 | PPARD (0.44) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL2740675 | 0.80 | TAS1R3 (0.44) | MTNR1ANQO2MTNR1BPPARD | |
| SCHEMBL7123434 | 0.79 | TUBB4A (0.48) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL2740671 | 0.77 | PPARD (0.44) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL5726773 | 0.77 | MTNR1B (0.52) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL6918438 | 0.77 | PPARD (0.44) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL15082055 | 0.75 | PPARD (0.42) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL15082056 | 0.73 | ESR1 (0.46) | MTNR1AMTNR1BSLC6A9PPARDESR1 | |
| SCHEMBL23366123 | 0.73 | PPARD (0.43) | MTNR1ANQO2MTNR1BSLC6A9PPARD | |
| SCHEMBL5462704 | 0.72 | ESR1 (0.47) | MTNR1BESR1ESR2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011446-A1 | INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |