SCHEMBL691850

SCHEMBL691850

C=Cc1cc(N)ccc1/N=N/c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.60
MAPK1 P28482 4/20 0.60
CYP3A4 P08684 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
TSHR P16473 2/20 0.60
ALDH1A1 P00352 2/20 0.60
TP53 P04637 1/20 0.60
MEN1 O00255 9/20 0.50
KMT2A Q03164 9/20 0.50
MAPT P10636 5/20 0.50
RAB9A P51151 2/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.45
NPC1 O15118 3/20 0.45
HBB P68871 2/20 0.44
CYP1A2 P05177 2/20 0.44
PTGS1 P23219 2/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691851 1.00 TDP1 (0.60) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL3312608 0.78 ALDH1A1 (0.50) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL28827287 0.78 ALDH1A1 (0.50) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL752490 0.77 TDP1 (0.96) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL940306 0.77 TDP1 (0.96) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL14437166 0.77 TDP1 (0.96) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL29539970 0.77 TDP1 (0.96) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL1756337 0.75 TDP1 (1.00) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
SCHEMBL29155112 0.75 TDP1 (0.93) TDP1MAPK1CYP3A4SMN1; SMN2TSHR
Lithium SCHEMBL30739531 0.75 TDP1 (0.93) TDP1MAPK1CYP3A4SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076833-A1 UV ABSORBER ALTERATION SYSTEM AND METHOD PERFECT IP LLC (US) 2026-03-19 US disclosed
EP-2421472-B1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY PERFECT IP LLC (US) 2017-05-17 EP disclosed
CN-105105918-A System for forming and modifying crystalline lens and crystalline lens formed by the same AAREN SCIENTIFIC INC 2015-12-02 CN disclosed
CN-105105869-A Method for forming and modifying crystalline lens AAREN SCIENTIFIC INC 2015-12-02 CN disclosed
US-9192292-B2 System for forming and modifying lenses and lenses formed thereby PERFECT IP, LLC (US) 2015-11-24 US disclosed
CN-102438549-B System for forming and modifying lenses and lenses formed thereby AAREN SCIENTIFIC INC 2015-07-15 CN disclosed
US-20150076723-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY PERFECT IP, LLC (US) 2015-03-19 US disclosed
US-8920690-B2 System for forming and modifying lenses and lenses formed thereby PERFECT IP, LLC (US) 2014-12-30 US disclosed
US-20140084501-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY PERFECT IP, LLC 2014-03-27 US disclosed
US-8568627-B2 Method for forming and modifying lenses PERFECT IP, LLC (US) 2013-10-29 US disclosed
US-20130103144-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. (US) 2013-04-25 US disclosed
EP-2542183-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY Aaren Scientific Inc. (US) 2013-01-09 EP disclosed
US-8292952-B2 System for forming and modifying lenses and lenses formed thereby AAREN SCIENTIFIC INC. (US) 2012-10-23 US disclosed
CN-102438549-A System for forming and modifying lenses and lenses formed thereby AAREN SCIENTIFIC INC 2012-05-02 CN disclosed
EP-2421472-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY Aaren Scientific Inc. (US) 2012-02-29 EP disclosed
WO-2011109039-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. (US) 2011-09-09 WO disclosed
US-20110212205-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. 2011-09-01 US disclosed
US-20110210459-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. 2011-09-01 US disclosed
WO-2010102155-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. (US) 2010-09-10 WO disclosed
US-20100228345-A1 SYSTEM FOR FORMING AND MODIFYING LENSES AND LENSES FORMED THEREBY AAREN SCIENTIFIC INC. (US) 2010-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076833-A1 UV ABSORBER ALTERATION SYSTEM AND METHOD APP, CRYZ, PTH1R TDP1 3586/4885MAPK1 2735/4885CYP3A4 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.