Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956433 | 0.90 | LMNA (0.39) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1035616 | 0.90 | KMT2A (0.40) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5160037 | 0.88 | KMT2A (0.39) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2497195 | 0.85 | HPGD (0.41) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL691974 | 0.83 | KMT2A (0.36) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1034491 | 0.83 | KMT2A (0.36) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL2064034 | 0.83 | ITGB1 (0.41) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6470163 | 0.82 | LPAR3 (0.40) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6467886 | 0.82 | LPAR3 (0.40) | LMNAMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6469685 | 0.82 | LPAR3 (0.40) | LMNAMEN1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | claimed |
| EP-2451847-B1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | IGM GROUP B V (NL) | 2021-11-24 | — | — | EP | disclosed |
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-9181358-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9181358-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2015-11-10 | — | — | US | disclosed |
| EP-2421903-B1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2014-11-19 | — | — | EP | disclosed |
| US-8883872-B2 | Polymer-bound bisacylphosphine oxides | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2012-06-07 | — | — | US | disclosed |
| EP-2451847-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| EP-2421903-A1 | POLYMER NANOPARTICLES | ETH Zurich (CH) | 2012-02-29 | — | — | EP | disclosed |
| WO-2011003772-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010121387-A1 | POLYMER NANOPARTICLES | ETH Zürich (CH) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024241-A1 | POLYMER NANOPARTICLES | POLQ, POLN, POLA1 | GABBR2 4315/4885GABBR1 4579/4885TSHR 4311/4885 |
| US-10023675-B2 | Polymer nanoparticles | POLQ, POLN, POLA1 | GABBR2 4315/4885GABBR1 4579/4885TSHR 4311/4885 |
| US-20120115963-A1 | POLYMER NANOPARTICLES | POLQ, POLN, POLA1 | GABBR2 4315/4885GABBR1 4579/4885TSHR 4311/4885 |
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | PHOSPHO1, PARG, PEBP1 | GABBR2 4372/4885GABBR1 4497/4885TSHR 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.