Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794175 | 0.76 | MAP4K4 (0.55) | MAP4K4MEN1KMT2AIMPDH2CYP11B1 | |
| SCHEMBL1446773 | 0.75 | MAP4K4 (0.49) | MAP4K4DGAT2MEN1KMT2ARHOA | |
| SCHEMBL6919267 | 0.75 | IMPDH2 (0.48) | MAP4K4DGAT2MEN1KMT2ARHOA | |
| SCHEMBL22209788 | 0.72 | MAP4K4 (0.48) | MAP4K4DGAT2MEN1KMT2ARHOA | |
| SCHEMBL17491538 | 0.72 | RHOA (0.40) | RHOAPDK2 | |
| SCHEMBL17491532 | 0.72 | RHOA (0.40) | RHOAPDK2 | |
| SCHEMBL17491466 | 0.72 | RHOA (0.40) | RHOAPDK2 | |
| SCHEMBL24746251 | 0.72 | CHRNB2 (0.55) | — | |
| SCHEMBL29505484 | 0.72 | CHRNB2 (0.55) | — | |
| SCHEMBL5408335 | 0.72 | CHRNB2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011457-A1 | 1-PHENYLPIPERIDIN-3-ONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2004-02-05 | — | — | WO | disclosed |