Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794175 | 0.77 | MAP4K4 (0.55) | IMPDH2MAP4K4MEN1KMT2ACYP11B1 | |
| SCHEMBL6918908 | 0.75 | MAP4K4 (0.47) | IMPDH2MAP4K4MEN1KMT2ACYP11B1 | |
| SCHEMBL17491405 | 0.71 | RHOA (0.35) | CYP11B1CYP11B2RHOAJAK3 | |
| SCHEMBL1446773 | 0.71 | MAP4K4 (0.49) | MAP4K4MEN1KMT2ADGAT2HDAC4 | |
| SCHEMBL5408330 | 0.70 | CHRNB2 (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL2158739 | 0.70 | KMT2A (0.75) | IMPDH2MAP4K4MEN1KMT2ACYP11B1 | |
| SCHEMBL1813296 | 0.69 | ALOX5 (0.46) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL22209788 | 0.68 | MAP4K4 (0.48) | IMPDH2MAP4K4MEN1KMT2ACYP11B1 | |
| SCHEMBL12301330 | 0.68 | ALOX5 (0.56) | MEN1KMT2A | |
| SCHEMBL10224171 | 0.67 | ALOX5 (0.41) | MEN1KMT2AHDAC4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011457-A1 | 1-PHENYLPIPERIDIN-3-ONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2004-02-05 | — | — | WO | disclosed |