Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923814 | 0.84 | NR1I2 (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL6925607 | 0.75 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL6827260 | 0.72 | NOTUM (0.38) | KDM4ELMNATP53CYP1A2ALOX12 | |
| SCHEMBL6827359 | 0.72 | PGR (0.38) | LMNANR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL6824827 | 0.72 | PGR (0.38) | LMNANR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL6923841 | 0.72 | KAT7 (0.35) | KDM4ELMNATP53CYP1A2ALOX12 | |
| SCHEMBL6827087 | 0.70 | PGR (0.39) | LMNA | |
| SCHEMBL6827215 | 0.70 | NR1I2 (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL6827816 | 0.70 | HTT (0.43) | KDM4ETP53 | |
| SCHEMBL6823849 | 0.68 | NR1I2 (0.42) | KDM4ELMNATP53CYP1A2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |